ABSTRACT
Objective To study the curative effect of high frequency oscillatory ventilation on acute respiratory distress syndrome (ARDS) caused by smoke inhalation injury in the lungs. Methods Fifty ARDS patients with lung injury caused by smoke inhalation were selected from 2010 to 2015. Patients were randomly divided into two groups, respectively choosing conventional mechanical ventilation or high frequency oscillatory ventilation. Results PaO2, PaCO2, and PaO2/FiO2were improved in both groups after the treatment (P＜0.05) . Patients in the treatment group improved significantly compared to those in the control group (P＜0.05) . The ventilation time and length of hospital stay reduced significantly in the treatment group (P＜0.05) . No significant difference was found in mortality and complication rates in both groups within 30 days (P＞ 0.05) . Conclusion High frequency oscillatory ventilation can effectively alleviate symptoms of ARDS caused by smoke inhalation injury in the lungs by improving oxygenation index. No obvious improvement is found in prognosis.